Style Switcher

Predefined Colors

Dr Hazwani Suhaimi Lecturer, Faculty of Integrated Technologies

About Me Publications

Dr Hazwani Suhaimi

Lecturer, Faculty of Integrated Technologies hazwani.suhaimi@ubd.edu.bn


ABOUT ME

I obtained my BEng in Chemical Engineering and MSc in Advanced Chemical Engineering with IT and Management from Loughborough University where I worked on a project on storage and preservation of cells for cell-based therapies. This sparked an interest in me to embark on a PhD journey where I was awarded a PhD degree on the glucose diffusivity in tissue engineering membranes and scaffolds and its implications for hollow fibre membrane bioreactor at Loughborough University (2015). The project focused on the investigation of glucose diffusion coefficient in cell-free and cell-seeded tissue engineering membranes and scaffolds in cell culture medium as well as non-dimensionalisation mathematical modelling using both MATLAB and experimental data where prediction of glucose concentration profiles inside the bioreactor was made possible. This would help to effectively design the bioreactor for producing 3D bone tissues. Upon completion, I am appointed to a lectureship in January 2016 at Faculty of Integrated Technologies, Universiti Brunei Darussalam in Chemical and Process Engineering.

RESEARCH INTERESTS

Tissue Engineering, Regenerative Medicine, Transport Process in Porous Media, Scaffold

16

Google Scholar Citations

2

Google Scholar h-index


FUTURE PROJECTS

Diffusion of lactic acid in cell-seeded tissue engineering scaffolds

While many studies in the literature assumed a similar value for the glucose diffusivity in both water and cell culture media (CCM), Suhaimi et al hypothesized the difference in the composition and hydrodynamic properties of both media should give different respective diffusivities. The results shown have proven the hypothesis to be correct. The glucose diffusivity in CCM has been found to be significantly reduced than the one in water due to CCM having a larger dynamic viscosity than water. Another reason may be due to the presence of extra components and therefore the difference in fluid properties of CCM. Although the result from this research does not exclusively apply to all other biological media/cultures since the variation in composition of media may imply a different diffusivity value, it does highlight the danger of assuming glucose diffusivity in CCM as equal to that in water. Similar to the self-diffusivity of glucose in CCM, the effective diffusivity for tissue engineering (TE) materials imbibed in CCM has also been found to be significantly smaller than those in water which is contrary to what have been generally assumed in the previous studies. This further proves that the presence of extra components is a contributing factor to a difference in the effective diffusivity value. Lactic acid is an example of a metabolic waste product produced by cells. As similar to the vascular system in vivo, we should mimic the system in such a way that the diffusion of lactate acid within the scaffold is also monitored. In this way, it may complete the biochemical communication and especially useful in developing a mathematical model that can simulate real situations.

Application invited for:


RECENT PUBLICATIONS

Suhaimi H, Das DB (2016) Glucose diffusion in tissue engineering membranes and scaffolds, Reviews in Chemical Engineering, Vol. 32, Issue 6, 629-650, DOI: 10.1515/revce-2015-0021
Suhaimi H, Das DB (2016) Glucose diffusivity in cell-seeded tissue engineering scaffolds, Biotechnology Letters, Vol. 38, Issue 1, 183-190, DOI: 10.1007/s10529-015-1958-2
Suhaimi H, Wang S, Das DB (2015) Glucose diffusivity in cell culture medium, Chemical Engineering Journal, Vol. 269, 323-327, DOI: 10.1016/j.cej.2015.01.130
Suhaimi H, Wang S, Thornton T, Das DB (2015) On glucose diffusivity of tissue engineering membranes and scaffolds, Chemical Engineering Science, Vol. 126, 244-256, DOI: 10.1016/j.ces.2014.12.029


TOP PUBLICATIONS

Suhaimi H, Wang S, Thornton T, Das DB (2015) On glucose diffusivity of tissue engineering membranes and scaffolds, Chemical Engineering Science, Vol. 126, 244-256, DOI: 10.1016/j.ces.2014.12.029
Suhaimi H, Wang S, Das DB (2015) Glucose diffusivity in cell culture medium, Chemical Engineering Journal, Vol. 269, 323-327, DOI: 10.1016/j.cej.2015.01.130
Suhaimi H, Das DB (2016) Glucose diffusivity in cell-seeded tissue engineering scaffolds, Biotechnology Letters, Vol. 38, Issue 1, 183-190, DOI: 10.1007/s10529-015-1958-2


RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

4 publications