Dr Minhaz Uddin Ahmed

minhaz.ahmed@ubd.edu.bn

Associate Professor, Faculty of Science



                                   

Dr. Minhaz Uddin Ahmed is an Associate Professor of Analytical Chemistry and Biotechnology at the Universiti Brunei Darussalam (UBD). He obtained his Ph.D. in Chemical Materials Science from Japan Advanced Institute of Science and Technology (JAIST) in 2008 under the supervision of Prof. Eiichi Tamiya and later worked as – JSPS post doctoral fellow at Osaka University, Japan (2008-2009, with Prof. Eiichi Tamiya), DARPA post doctoral research associate at Duke University, USA (2009-2010, with Prof. April S. Brown) and NSERC post doctoral fellow at INRS-EMT, Canada (2010-2012, with Prof. M. Zourob). His research interests are in the areas of biosensors and diagnostic technologies, and applications to nanobiotechnology, clinical and environmental chemistry. Dr Ahmed is an alumnus of JAIST and a prestigious young participant/fellow of 57th Lindau Nobel Laureate Meeting for Physiology and Medicine, 2007, Germany. In 2008, he was awarded with the prestigious Japanese Society for the Promotion of Science (JSPS) young scientist award to work in Graduate School of Engineering of Osaka University. In 2009, he was awarded with the United States Defence Advanced Research Project Agency (DARPA) post doctoral fellowship to work at Pratt School of Engineering of Duke University.
He started his own research group in 2012 at science faculty-laboratory for Biosensors, Applied Biotechnology and Halal Science. Apart from his research group, he has been appointed as a "Research Lead" for the BEDB-BRISc funded VBL (Venture business laboratory) at UBD. He is currently supervising a number of graduate and undergraduate students in his laboratory. He is also involved in teaching courses like Biosensors, Biochips and Nanobiotechnology, Modern Analytical Techniques, Nutritional Biochemistry and Food Chemistry and Chemical Analysis of Foods.
His researches are to develop reliable and simple methodologies that could allow bioanalytical detection to be carried out for various applications, particularly on the aspects of food safety, healthcare and environmental protection which deserve public awareness. He has published numerous articles on the reputed journals of Bioanalytical chemistry like Biosensors and Bioelectronics, Analytical Chemistry, Analyst , Critical review in Biotechnology, Food Chemistry, RSC Advances etc. He is frequently invited to write reviews in top international journals like Biosensors and Bioelectronics which is the principal international journal devoted to research, design development and application of biosensors and bioelectronics in the world.
Dr. Ahmed’s works are currently funded by Brunei Research Council (BRC-10 and BRC-4), Graduate Research Studentships, Cross boundary research programme of Osaka University. He has also active research collaboration with Osaka University, JAIST, Cranfield University of UK, Harvard University of US, INRS-EMT of Canada, University of Chittagong of Bangladesh, and Alfaisal University of Saudi Arabia.
Currently, Dr Ahmed is also serving as an Associate Editor of the Q1 journal “RSC Advances” published by the Royal Society of Chemistry (RSC), UK. He is also working as a member of the editorial board for the Journal "Sensor International" and ''Biointerface Research in Applied Chemistry''.

Dr Minhaz's Publons ID: PUBLONS LINK for REVIEW AND EDITORIAL WORKS:
publons.com/a/1301472/

Associate Editor: RSC Advances, UK (Q1 Journal) 2015-to date.
Associate Editor: Scientia Bruneiana, 2016- to date.
Editorial Board Member: Sensor International, 2018- to date.
Editorial Board Member: Biointerface Research in Applied Chemistry, 2019- to date.
Editorial Board Member: Bioengineering International. 2019- to date.


Teaching history:
SC 4363 Modern Analytical Techniques
SC 4368 Biosensors Biochips and Nanobiotechnology
SC 4366 Food Chemistry and Chemical Analysis of Food
SB 4314 Biotechnology
SB 4340 Nutritional Biochemistry
SR 5101 Advanced Research Skill

EDUCATION

Ph.D. in Chemical Materials Science from Japan Advanced Institute of Science and Technology (JAIST)
(with 18 months of full-time attachment at Graduate School of Engineering, Osaka University, Japan)

Post Doctoral Trainings:
JSPS Fellow: Osaka University: 2008-2009, Japan
DARPA Research Associate: Duke University: 2009-2010, USA
NSERC Fellow: INRS-EMT: 2010-2012, Canada

RESEARCH INTERESTS

Next Generation Nucleic Acids and Protein Biosensors
Novel Chemical Biology and Biomaterials Approaches
Point-of-Care (POC) Micro Devices
Agro/Food based Applied Biotechnology
DNA/Protein Bioinformatics and Bioengineering

FUTURE PROJECTS

Food (including Halal food) Analysis

As an Islamic country, Brunei Darussalam strives to implement the production of Halal products, especially food, in accordance to Islamic dietary law. However, majority of the commercial food products in Brunei are yet being imported from abroad. Hence, there is a risk on food frauds to be aware of by the public. For example, contamination of food products by traces of pork material.Currently, we are working on a detection system based on Real Time Polymerase Chain Reaction (RT-PCR) or Loop-Mediated Isothermal Amplification (LAMP) that could allow detection of low abundance pork DNA in food samples. In addition, we are also striving to develop novel methodologies based on electrochemical and colorimetric detection systems. In parallel, we are also attempting to improve the efficacy of each methodology by implementing nanotechnology on catalytic mechanisms, biochips production and so on, as well as to develop a detection system that can be utilized for on-site monitoring. Putting it together, our goal is to develop highly sensitive, highly specific, rapid, portable and robust detection systems that can be employed for on-site monitoring during Halal food inspection.Please email: <minhaz.ahmed@ubd.edu.bn> with your interests for updated proposals.


Applications Invited
B.Sc./MSc/Ph.D./Internship

Microbial (Bacterial/Virus) analysis

By targeting specific DNA regions of pathogens, RT-PCR can be employed for the detection of foodborne and waterborne pathogens for microbial analysis. Currently, we are in collaboration with the Institute of Health Science (IHS) to develop a detection system based on RT-PCR technique for the detection of bacteria, including Bacillus cereus, Legionella pneumophila and Staphylococcus aureus. Furthermore, we are also developing new strategies using tablet blister packs for the detection of White spot syndrome virus (WSSV), which has been associated with shrimps infection harvested from South China Sea that has caused huge economic losses.With the increase of undeclared importation of plants and planting materials from neighboring countries, local plants are more susceptible to dangerous diseases caused by microbes infections. Hence, we are also planning to develop strategies that can allow detection of harmful microbes to identify infected plants in counter for further damages. Please email: <minhaz.ahmed@ubd.edu.bn> with your interests for updated proposals.


Applications Invited
B.Sc./MSc/Ph.D./Internship

Clinical diagnostics

Cancer is one of the leading causes of death not only in Brunei Darussalam, but also globally. human chorionic gonadotropin (hCG)is a hormone commonly found in the serum of pregnant women. Presence of significant high level of hCG in men and non-pregnant women can serve as an indication for cancer development. Previously, our laboratory has conducted studies on the detection of hCG based on nanotechnology and electrochemical biosensing approach. By electrochemically quantifying the level of gold nanoparticles that are conjugated to anti-hCG antibody, we could indirectly quantify the level of hCG in serum. Using this strategy as template, we are striving to bring this methodology toward the detection of other biomarkers like sIgA (Saliva), C-reactive protein (CRP), Interleukin 1 Beta, Prostate specific antigen (PSA) etc. Please email: <minhaz.ahmed@ubd.edu.bn> with your interests for updated proposals.


Applications Invited
B.Sc./MSc/Ph.D./Internship
75

Scopus Publications

2274

Google Scholar Citations

24

Google Scholar h-index

39

Google Scholar i10-index

Scopus Publications

RECENT PUBLICATIONS

See full list@: https://www.scopus.com/authid/detail.uri?authorId=7402830936
Azureen Mohamad, Mohammed Rizwan, Natasha Ann Keasberry, Anh Son Nguyen, Tran Dai Lam, Minhaz Uddin Ahmed, Gold-microrods/Pd-nanoparticles/Polyaniline-Nanocomposite-Interface as a Peroxidase-Mimic for Sensitive Detection of Tropomyosin, Biosensors and Bioelectronics, 155, 1, 112108 (2020).

Juthi Adhikari, Natasha Ann Keasberry, Abdul Hanif Mahadi, Hiroyuki Yoshikawa, Eiichi Tamiya and Minhaz Uddin Ahmed, A highly sensitive label free electrochemiluminescence immunosensor for the detection of CKMB using CNOs/Fe/Au/Chi nanocomposite on SWCNTs modified screen-printed electrode, RSC Advances, 9, 34283-34292 (2019).

Nur Diyanah Matassan, Mohammad Riwan, Noor Faizah Mohd Naim and Minhaz Uddin Ahmed, Graphene Nanoplatelets-Based Aptamer Biochip for The Detection of Lipocalin-2, IEEE Sensors, 19, 21, 9592-9599 (2019).

Mohammad Rizwan, Muhammad Hazmi, Syazana Abdullah Lim and Minhaz Uddin Ahmed, Novel and highly sensitive electrochemical detection of human chorionic gonadotropin hormone using polyethylene glycol /Carbon nano-onions/Gold nanoparticles Nanocomposite, Intl J of Electroanalytical Chemistry, 833, 462-470 (2019).

Azureen Mohammad, Hui sian Teo, Natasha Ann Keasberry and Minhaz Uddin Ahmed, Recent developments in colorimetric immunoassays using nanozymes and plasmonic nanoparticles, Critical Review in Biotechnology, 39:1, 50-66 (2019).

Mohammed Rizwan, Syazwani Elma, Syazana Abdullah Lim and Minhaz Uddin Ahmed, Development of AuNPs/SWCNTs/CNO/CS Modified Electrochemical sensors for the detection of Carcinoembryonic Antigen, Biosensors and Bioelectronics, 107 (1) 211-217 (2018).

IMMUNOSENSORS (2019)
Editors: Minhaz Uddin Ahmed et al.
Published by Royal Society of Chemistry, UK as RSC’s series: Detection Science
Publication: August 2019. ISBN: 978-1788014373
* Principal and Corresponding Editor

TOP PUBLICATIONS

Minhaz Uddin Ahmed, M. Mosharraf Hossain, Mohammedali Safavieh, Yen Lu Wong, Ibrahim Abd Rahman, Mohammed Zourob and Eiichi Tamiya, Toward the development of smart and low-cost point-of-care biosensors based on screen-printed electrodes. Critical Review in Biotechnology: 36(3):495-505. (2016). [Impact Factor: 7.83]

Mohammad Rizwan, David Koh, Marselia H Booth and Minhaz Uddin Ahmed, Combining Au-PEG nanocomposites and carbon nanofiber electrodes to develop a highly sensitive salivary secretory Immunoglobulin A immunosensor. Sensors and Actuators B Chemical, 255, 557-563, (2018). [Impact factor 6.39]

Sharmili Roy, Sim Wei Xiao, Jean Liew Zhi Ying, Mohammedali Safavieh, Minhaz Uddin Ahmed, A novel and sensitive loop-mediated isothermal amplified DNA detection in solution using luminophore dye. Biosensors and Bioelectronics, 86, 346–352 (2016). [Impact factor 9.5]

Hamadah Nur Lubis, Noor Faizah Mohd-Naim, Nur Nazurah Alizul, Minhaz Uddin Ahmed, From market to food plate: current technology and innovations in Halal food analysis. DOI: 10.1016/j.tifs.2016.10.024; Trends in Food Science and Technology (2016). [Impact factor 6.6]

Syazana Abdullah Lim and Minhaz Uddin Ahmed, A carbon nanofiber-based label-free voltammetric immunosensor for high sensitive detection of recombinant bovine somatotropin. Biosensors and Bioelectronics; 70, 48-53 (2015) [Impact factor 9.5]

GRANT DETAILS

2020-2022: UBD Research Grant as a Principal Investigator; Grant# FIC25; Nanoscaled aptasensors for the detection of multiple biomarkers (Grant amount, 69,500.00 BND: for 2 years).
2020-2022: ASEAN-India S&T Development Fund (AISTDF); as a co-Principal Investigator; Grant# CRD/2019/000158 (Grant amount; 48,28,192 INR: for 2 years).
2018-2020: UBD Research Grant as a Principal Investigator; Grant# FIC10; The development of novel nanostructured biosensors for multiple food allergens (Grant amount, 60,900.00 BND: for 2 years).
2014-2017: Brunei Research Council’s grant; BRC-10 as a Principal Investigator; A versatile signal amplification strategy for biomarkers identification using flexible substrates (Grant amount 2.4 million BND; for 4 years).
2015-2017: Brunei Research Council’s grant; BRC-4 as a co-Principal Investigator; Multidisciplinary research on salivary biomarkers. (Grant amount 1.2 million BND: for 2 years).
2013-2014: UBD Research Grant as a Principal Investigator; Graphene-based platform for the detection for porcine biomarkers (Grant amount 21700.00 BND: for 2 years).
2008-2010: Grant-In-Aid: as a co-P.I.: Japan Society for the Promotion of Science (JSPS) for Scientific Research. (Grant amount 1.5 million Japanese Yen: for 2 years).

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

AWARDED PATENTS:

2. USA Patent no: US10605806B2: Issue date: 31/03/2020; Electrochemical immunosensor and method of use for analyte detection.
1. USA Patent no: US10465244B2: Issue date: 05/11/2019; Electrochemical DNA Biosensor using graphene biochip for species identification.

PATENTS PENDING:
5. Minhaz Uddin Ahmed, Mohammad Rizwan, and Noor Faizah Mohd-Naim, Nanocomposite modified CdSe QDs electrode for a label-free and highly sensitive ECL immunosensor, US and Brunei Patent Pending (2017).
4. Minhaz Uddin Ahmed, Mohammad Rizwan and David Koh, A nanocomposite based immunosensor for detecting biomarker and method thereof, US and Brunei Patent Pending (2017).
3. Minhaz Uddin Ahmed and Sharmili Roy, System and method for immobilization free electrochemiluminescence DNA detection using a luminophore dye for multi-species detection, Brunei file# BN/N/2016/0064. (2016)
2. Minhaz Uddin Ahmed and Sharmili Roy, System and method for immobilization free electrochemiluminescence DNA detection using a luminophore dye for multi-species detection, United States Patent: US2018/0037944 A1.(2018).
1. Minhaz Uddin Ahmed and Syazana Abdullah Lim, Electrochemical immunosensor and method of use for analyte detection, United States Patent Pub.: US201815131438 (2016).

CONSULTANCY

Associate Editor: RSC Advances (2015-to date), Q1 Journal of Royal Society of Chemistry, UK. IF 3.2.
Associate Editor: Scientia Bruneiana (2017-to date)
Editorial Board Member: Sensor International, Elsevier-Science direct Journal (2019-to date)
Editorial Board Member: Biointerface Research in Applied Chemistry (2019-to date)
Editorial Board Member: Bioengineering International.(2019-to date)

Industry, Institute, or Organisation Collaboration

Imperial College, UK
Cranfield University, UK
Harvard University, USA
Alfaisal University, Saudi Arabia
Universiti Technology Brunei
University of Chittagong, Bangladesh
INRS-EMT, University of Quebec, Canada
CIGIT of Chinese Academy of Sciences, China
Vietnam Academy of Sciences, Vietnam
National University of Singapore, Singapore
National Institute of Technology, Karnataka, India

SOCIAL, ECONOMIC, or ACADEMIC BENEFITS

We are aiming at developing reliable and yet simple methodologies that could allow biological detection to be carried out for various applications, particularly on the aspects of food safety, healthcare and environmental protection which deserve public awareness.