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Dr. Abdullahi Abubakar Senior Assistant Professor, Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences

About Me Publications

Dr. Abdullahi Abubakar

Senior Assistant Professor, Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences abubakar.abdullahi@ubd.edu.bn


ABOUT ME

Dr. Abdullahi Abubakar is a molecular and computational biologist with special interest on proteins implicated in cancers. He graduated with MBBS and was a Registrar of the West African College of Surgeons where he started training in general surgery. Due to his passion for basic medical science research, Dr. Abdullahi left surgery training mid-way and went and did M.Sc. Human anatomy and PhD Molecular Medicine.
His research interest is high-throughput RNA silencing of genes implicated in the various cancers as well as structure-based drug design studies of proteins linked to various cancers. The ultimate aim of his research is to develop experimental and pre-clinical cancer targeted therapy models by developing drugs targeting proteins linked to cancers.

EDUCATION

• PhD Molecular Medicine • National University of Malaysia (University Kebangsaan Malaysia), Malaysia.

• MSc. Human Anatomy • Usmanu Danfodiyo University Sokoto, Nigeria.

• MB, BS (Bachelor of Medicine, Bachelor of Surgery) University of Maiduguri, Nigeria.

• Primaries • West African College of Surgeons.

RESEARCH INTERESTS

The following are my research interests:

1. Interests in computational and structural biology of proteins implicated in cancers including phosphatidylinositol-3-kinase beta, B-Cell lymphoma 2 (BCL-2) and B-Cell lymphoma extra large (BCL-xL) proteins and apoptosis antagonizing factor gene (AATF).

2. Interest in high-throughput gene silencing using short interfering RNA (siRNA) with more emphasis of cancer targeted therapies.

3. I have interest in protein crystallization techniques, bio-processing and fermentation strategies focusing on proteins expression in E. Coli, Pasteurella Multocida in bioreactors for subsequent protein structural biology studies using X-ray diffraction data facilities and synchrotron facilities of our collaborating institutions.

4. I have interest in the analysis of protein X-ray diffraction data from reduction to scaling, protein model building, data refinement and protein analysis using MOSFLM, RefMac, Mercury, coot, phaser and many others CCP4 software package.

47

Google Scholar Citations

4

Google Scholar h-index

2

Google Scholar i10-index


RECENT PUBLICATIONS

• A. D. Abdullahi, Jamal, R. A., & Harun, R. A Protein Modelling and Molecular Docking study to enable the Design of Apoptosis Antagonizing Transcription Factor (AATF) Docking Hits. INPRESS: Submitted to Medicinal Chemistry Research (Springer).
• A. D. Abdullahi, Aung, S., Chyang, K. A. P. J., Jamal, R. A., & Harun, R. Identification of Therapeutic Targets for Small Cell Lung Cancer using In Silico Analysis and RNA Interference. INPRESS.
• A. S. Nadiahanis, Abdualkader, M. A., Mohamed, F. & A. D. Abdullahi. Designing Novel PI3K-Γ Inhibitors through Group-Based Quantitative Structural Activity Relationship and Molecular Docking. INPRESS: Submitted to Interdisciplinary Sciences: Journal of Computational Life Sciences (Springer).
• A. D. Abdullahi, Abdualkader, A. M., Samat, N. H. B. A., & Ingale, K. B. The Application of Group-based QSAR and Molecular Docking in the Design of Novel IGF-1R Antagonists. Tropical Journal of Pharmaceutical Research, 14(6), 941-951, ISSN: 1596-5996, 2015.
• A. D. Abdullahi, Nadiahanis, A. M. A. A., Yauri, B. Y. M., Mohamed, F., Kasmuri, A., Aljarbou, A., Altuwaijri, S., Harun, R., & Helal Uddin, A. B. M. Molecular Docking and Group-based QSAR in the Design of Novel p70 Ribosomal S6 Kinase (p70S6K) Inhibitors. Journal of Applied Pharmaceutical Science, 4(6), 16-24, 2014.
• Nadiahanis, A. S., Abdualkader, M. A., Mohamed, F., & A. D. Abdullahi. Group-based Quantitative Structure Activity Relationship (G-QSAR) Analysis and Molecular Docking of B-cell Lymphoma Extra-large (Bcl-xl) Inhibitors. International Journal of Pharmacy and Pharmaceutical Sciences, 6(5), 2014.
• Nadiahanis, A. S., Mohamed, F., & A. D. Abdullahi. Group-based Quantitative Structure-Activity Relationship (G-QSAR) Analysis and Molecular Docking of B-Cell Lymphoma 2 (BCL-2) Inhibitors. Journal of Science and Technology in the Tropics (JOSTT); Special Issue Supplement, 2013.
• Merzouk, A., Ghawi, A. M., Abdualkader, A., A. D. Abdullahi & Alaama, M. Anticancer Effects of Medical Malaysian Leech Saliva Extract (LSE). Pharm Anal Acta S, 15(2), 15:2, 2012.
• Ibrahim, K., A. D. Abdullahi, Leong, N. C., Murad, N. A. A., Mokhtar, R. J. N. N., Wan Ngah, W. Z., & Harun, R. In silico Homology Modelling and Identification of Tousled-like Kinase 1 Inhibitors for Glioblastoma Therapy via High-throughput Virtual Screening Protein-ligand Docking. INPRESS
• Malami, S. A., Pindiga, U. H., Abimiku, B. A., Dauda, A. M., Mungadi, I. A., A. D. Abdullahi, Dauda, A., & Sahabi, S. M. A Descriptive Retrospective Study of the Pattern of Malignant Diseases in Sokoto, Northwestern Nigeria 1999-2004. Journal of Medical Sciences, 7(6), 1033-1038, 2007.


TOP PUBLICATIONS

• A. D. Abdullahi, Abdualkader, A. M., Samat, N. H. B. A., & Ingale, K. B. The Application of Group-based QSAR and Molecular Docking in the Design of Novel IGF-1R Antagonists. Tropical Journal of Pharmaceutical Research, 14(6), 941-951, ISSN: 1596-5996, 2015.
• A. D. Abdullahi, Nadiahanis, A. M. A. A., Yauri, B. Y. M., Mohamed, F., Kasmuri, A., Aljarbou, A., Altuwaijri, S., Harun, R., & Helal Uddin, A. B. M. Molecular Docking and Group-based QSAR in the Design of Novel p70 Ribosomal S6 Kinase (p70S6K) Inhibitors. Journal of Applied Pharmaceutical Science, 4(6), 16-24, 2014.
• Nadiahanis, A. S., Abdualkader, M. A., Mohamed, F., & A. D. Abdullahi. Group-based Quantitative Structure Activity Relationship (G-QSAR) Analysis and Molecular Docking of B-cell Lymphoma Extra-large (Bcl-xl) Inhibitors. International Journal of Pharmacy and Pharmaceutical Sciences, 6(5), 2014.
• Nadiahanis, A. S., Mohamed, F., & A. D. Abdullahi. Group-based Quantitative Structure-Activity Relationship (G-QSAR) Analysis and Molecular Docking of B-Cell Lymphoma 2 (BCL-2) Inhibitors. Journal of Science and Technology in the Tropics (JOSTT); Special Issue Supplement, 2013.
• Merzouk, A., Ghawi, A. M., Abdualkader, A., A. D. Abdullahi & Alaama, M. Anticancer Effects of Medical Malaysian Leech Saliva Extract (LSE). Pharm Anal Acta S, 15(2), 15:2, 2012.