Dr Suwarni Hj Mohd Diah

EDUCATION

Bachelor of Biotechnology (Hons) from University of Queensland, Australia and PhD in Medical Science from Kagawa University, Japan.

RESEARCH INTERESTS

- Rare sugar study- Studying the anti-cancer effects of D-allose in cancer cell lines, clinical trial of D-allulose to study its anti-diabetic effect in Bruneians.
- Healthy food development- Development of Brunei traditional food using rare sugar D-allulose, which has anti-diabetic and anti-obesity properties.
- Brunei traditional plant study- studying different types of Brunei traditional plants for anti-diabetes and anti-cancer properties.
- Neuroinfection study in Brunei- Development of the blood brain barrier (primary and cell line) and studying the pathogenesis of dengue and bacterial meningitis.

RECENT PUBLICATIONS

Rahman, N.A., Rasil, A.N.H.M., Meyding-Lamade, U., Craemer, E.M., Diah, S., Tuah, A.A., Muharram, S.H., April 2016. Immortalized endothelial cell lines for in vitro blood-brain barrier models: A systematic review. Brain Res. 1642, 532–545. doi:10.1016/j.brainres.2016.04.024

Idris, F., Muharram, S.H., Diah, S., April 2016. Glycosylation of dengue virus glycoproteins and their interactions with carbohydrate receptors: possible targets for antiviral therapy. Arch. Virol. 161, 1751–1760. doi:10.1007/s00705-016-2855-2

Nurul Adhwa Rahman, Aishah Sharudin, Suwarni Diah, Siti Hanna Muharram (2017) Serotyping of Brunei pneumococcal clinical strains and the investigation of their capability to adhere and invade a brain endothelium model. Microbial Pathogenesis. 2017 Sep; 110:352-358. doi: 10.1016/j.micpath.2017.07.021

TOP PUBLICATIONS

Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. Diah S, Zhang GX, Nagai Y, Zhang W, Gang L, Kimura S, Hamid MR, Tamiya T, Nishiyama A, Hitomi H.
Experimental Cell Research. 2008 Dec 10;314(20):3654-62.

Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. Fan YY, Kohno M, Nakano D, Ohsaki H, Kobori H, Suwarni D, Ohashi N, Hitomi H, Asanuma K, Noma T, Tomino Y, Fujita T, Nishiyama A.
Journal of Hypertension. 2010 May;28(5):1034-43.

Short-term calorie restriction in early life attenuates the development of proteinuria but not glucose intolerance in Type 2 Diabetic OLETF rats.
Daisuke Nakano, Suwarni Diah, Kento Kitada, Hirofumi Hitomi, Hirohito Mori, Tsutomu Masaki, Hiroyuki Kobori, and Akira Nishiyama. International Scholarly Research Network ISRN Endocrinology, Volume 2011 (2011).

Immortalized endothelial cell lines for in vitro blood-brain barrier models: A systematic review. Rahman, N.A., Rasil, A.N.H.M., Meyding-Lamade, U., Craemer, E.M., Diah, S., Tuah, A.A., Muharram, S.H., April 2016. Brain Res. 1642, 532–545. doi:10.1016/j.brainres.2016.04.024

Glycosylation of dengue virus glycoproteins and their interactions with carbohydrate receptors: possible targets for antiviral therapy. Idris, F., Muharram, S.H., Diah, S., April 2016. Arch. Virol. 2016 Jul;161(7):1751-60. doi:10.1007/s00705-016-2855-2