Mas Rina Wati Haji Abdul Hamid

Dr Mas Rina Wati is a senior lecturer at PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam. She taught molecular genetics to medical, biomedical and other healthcare professional students. She had been a programme leader for graduate studies and had also been in other administrative post during the early years of the institute.
She obtained her Ph D in molecular microbiology at Heriot-Watt University, Edinburgh, Scotland. She then did a 5 year postdoctoral fellowship at the Institute of Molecular and Cell Biology, Singapore where she started to develop interest in working with the mammalian system. It was at the Department of Biochemistry, University of Queensland, Australia that she had the opportunity to work with the breast cancer gene, BRCA, when she did a sabbatical for year. He research interest is currently on genetics of breast cancer looking specifically at the BRCA genes in Brunei breast cancer. She is also interested in other cancers such as colorectal and lung cancers and believe that translational research is the way forward for improving clinical services and human health and well-being in Brunei. She has publications in internationally-peer reviewed journals and has presented at conferences and symposiums, both national and international.

EDUCATION

Ph D Molecular Microbiology
BSc (Hons) Microbiology

RESEARCH INTERESTS

Genetics of breast cancer and related cancers
SYK and apoptosis

FUTURE PROJECTS

RECENT PUBLICATIONS

(1) Yu Hao Han, Mas RW Abdul Hamid, Pemasiri Upali telisinghe, Juniadah Binti Haji Hussin and Mohamed Mabruk
Overexpression of EGFR Protein in Bruneian Lung Cancer Patients
Asian Paciifc Journal of Cancer Prevention (2015) 16 (1), 233- 237

(2) Tushar Kanti Das, Mas RW Abdul Hamid, Tuhin Das and Kaneez Fatima-Shad
Potential of glycowithanolides from Withania somnifera (Ashwagandha) as therapeutic agents for the treatment of Alzheimer’s Disease (AD)
World Journal of Pharmaceutical Research (2015) 4 (6): 16-38

(3) Simpson, KJ, Wati, MR, Deans AJ, Lindeman GJ and Brown MA
MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development
International Journal of Developmental Biology (2004) 48:675-678

(4) Brown, MA, Nicolai H, Howe, K, Katagiri, T, Lalani, E-N, Simpson, KJ, Manning NW, Deans AJ, Chen, P, Khanna KK, Wati, MR, Griffiths BL, Xu, C-F, Stamp, GWH and Solomon, E.
Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice.
Transgenic Research (2002) 11:467-478

(5) Reiner U Janicke, Michael L Sprengart, Mas R Wati and Alan G Porter
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
Journal of Biological Chemistry, 273 (1998) 9357-9360

TOP PUBLICATIONS

(1) Reiner U Janicke, Michael L Sprengart, Mas R Wati and Alan G Porter
Caspase-3 is required for DNA fragmentation and morphological changes associated with
apoptosis
Journal of Biological Chemistry, 273 (1998) 9357-9360

(2) Mas R Wati, Thirumaran Thanabalu and Alan G Porter
Gene from tropical Bacillus sphaericus encoding a protease closely-related to subtilisins from Antarctic bacilli.
Biochimica et Biophysica Acta, 1352 (1997) 56-62

(3) Brown, MA, Nicolai H, Howe, K, Katagiri, T, Lalani, E-N, Simpson, KJ, Manning NW, Deans AJ, Chen, P, Khanna KK, Wati, MR, Griffiths BL, Xu, C-F, Stamp, GWH and Solomon, E.
Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice.
Transgenic Research (2002) 11:467-478

(4) Tushar Kanti Das, Mas Rina Wati and Kaneez Fatima-Shad
How oxidative stress gated by Fenton and Haber-Weiss reactions leads to Alzheimer’s Disease
Archives of Neuroscience (2014)

(5) Simpson, KJ, Wati, MR, Deans AJ, Lindeman GJ and Brown MA
MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development
International Journal of Developmental Biology (2004) 48:675-678